Wyle is the only original cast member left in the drama
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ER's longest serving cast member Noah Wyle has hinted he may hang up his stethoscope.
Wyle, who has played Dr John Carter since ER began in 1994, said on a US cable television show he planned to leave the hit show.
The Emmy-nominated actor said he had an "urge to scratch a different kind of itch" in his career.
But a spokesman for Wyle said the actor's position was a "wait and see" one, rather than definite.
Professional life
Wyle had responded with a quick "yep" when asked on E! News Live whether he intended to leave the hospital drama.
"I've just got other stuff going on in my life right now," he explained.
"I've got a son. I've got family and friends that said goodbye to me 12 years ago and are wondering when I'm coming back."
Los Angeles-based publicist, Eddie Michaels, said Wyle's comments conveyed his personal and professional stage in life.
Emmy awards
He added that Wyle has had no formal talks with the show's producers about his future on ER, despite the fact his contract is due to end this season.
Michael's said: "Where this leads in the next few months, we'll just have to wait-and-see.
"What he was really saying is that he's thought about it, and thought about it in a real, meaningful way."
ER became an instant hit and it went on to win several prestigious Emmy awards.