Health minister Mike O'Brien says primary care trusts have a legal responsibility to ensure patients receive high quality out-of-hours GP care.
His comments follow the publication of an interim report by the Care Quality Commission, which says out-of-hours care provided by private GP companies is not being checked thoroughly enough.
The review was prompted by the death of David Gray, who was accidentally killed by a German doctor working his first out-of-hours shift in Britain.
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